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Patients are actor portrayals.
Physician is a pediatric endocrinologist.
An early diagnosis of ALD can save lives1
ALD is a rare, X‑linked metabolic disorder characterized by an accumulation of very-long chain fatty acids (VLCFAs) in various parts of the body.2,3 As it is X‑linked, this disorder affects males more severely.2 Without early detection, ALD can progress to a serious, life-threatening condition called cerebral ALD, which can lead to irreversible brain damage.1,2,4,5
As part of the initial evaluation of preadolescent boys with primary adrenal insufficiency, the Endocrine Society Clinical Practice Guidelines recommend screening for elevated VLCFA levels in plasma in order to detect the possibility of ALD, which may be further confirmed through genetic testing.2,6Measure VLCFA levels in plasma
Consult and collaborate to monitor progression
Vigilant observation and timely intervention are crucial for improved outcomes1
Monitoring disease progression to cerebral ALD relies on an integrated care team, including both pediatric endocrinologists and neurologists who specialize in ALD.1
Refer your patient to a neurologist or ALD specialist, so that they are able to monitor for disease progression to cerebral ALD and provide appropriate care.1Monitoring ALD